Csta1 Gene Summary [Mouse]
Predicted to enable cysteine-type endopeptidase inhibitor activity and protease binding activity. Predicted to be involved in several processes, including keratinocyte differentiation; negative regulation of peptidase activity; and peptide cross-linking. Predicted to be located in several cellular components, including cornified envelope; extracellular space; and nucleoplasm. Predicted to be part of peptidase inhibitor complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in peeling skin syndrome 4. Orthologous to human CSTA (cystatin A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Csta1 |
| Official Name | cystatin A1 [Source:MGI Symbol;Acc:MGI:3524930] |
| Ensembl ID | ENSMUSG00000034362 |
| Bio databases IDs | |
| Aliases | cystatin A1 |
| Synonyms | 2010005H15Rik, Csta, Csta2, Cstdc4, cystatin A, cystatin A1, cystatin A family member 2, Cystatin-alpha, cystatin domain containing 4, Cystatin-α, EG433016, Gm5483 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Csta1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CY
- cysteine protease inhibitor activity
- protease binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- Extracellular Space
- cytosol
- nucleoplasm