Details
| Type | Mitochondrial Transfer RNA |
| Official Symbol | MT-TH |
| Official Name | mitochondrially encoded tRNA-His (CAU/C) [Source:HGNC Symbol;Acc:HGNC:7487] |
| Ensembl ID | ENSG00000210176 |
| Bio databases IDs | |
| Aliases | mitochondrially encoded tRNA-His (CAU/C) |
| Synonyms | mt-Th-201, tRNA-His, TRNH |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MT-TH often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- triplet codon-amino acid adaptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- myelodysplastic syndrome
- MELAS syndrome
- pigmentary retinopathy and sensorineural deafness
- MERRF/MELAS overlap syndrome
- mitochondrially inherited nonsyndromic sensorineural deafness
- mitochondrial disorder
- idiopathic mitochondrial dilated cardiomyopathy
- hypertrophic mitochondrial cardiomyopathy
regulated by
- bardoxolone methyl
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria