Mrgprx1 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be active in plasma membrane. Orthologous to several human genes including MRGPRX3 (MAS related GPR family member X3) and MRGPRX4 (MAS related GPR family member X4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mrgprx1
Official Name
MAS-related GPR, member X1 [Source:MGI Symbol;Acc:MGI:3033139]
Ensembl ID
ENSMUSG00000070552
Bio databases IDs NCBI: 404242 Ensembl: ENSMUSG00000070552
Aliases MAS-related GPR, member X1
Synonyms MAS related GPR family member X1, MAS-related GPR, member X1, Mgrg2, MrgC, MrgC11, Mrgprc, Mrgprc11, Mrgprx4, Snsr, Snsr1
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrgprx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (rhodopsin family)
  • seven-transmembrane G protein-coupled receptor superfamily
  • transmembrane receptor

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • Der p 1
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

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