Ces1a Gene Summary [Rat]
Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in lipid catabolic process. Predicted to be active in endoplasmic reticulum and lipid droplet. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ces1a |
| Official Name | carboxylesterase 1A [Source:RGD Symbol;Acc:1583671] |
| Ensembl ID | ENSRNOG00000039725 |
| Bio databases IDs | |
| Aliases | carboxylesterase 1A |
| Synonyms | carboxylesterase 1A, Ces1l, EG244595, Gm4976, LOC683132 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ces1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- carboxylic ester hydrolase
- Carboxylesterase family
- sterol esterase
- alpha/beta hydrolases
- enzyme
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- lipid droplets