Dear Gene Summary [Rat]
Enables angiotensin type II receptor activity and endothelin receptor activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Orthologous to human FBXW7-AS1 (FBXW7 antisense RNA 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dear |
| Official Name | dual endothelin 1, angiotensin II receptor [Source:RGD Symbol;Acc:1303105] |
| Ensembl ID | ENSRNOG00000033147 |
| Bio databases IDs | |
| Aliases | dual endothelin 1, angiotensin II receptor |
| Synonyms | DEspR, dual endothelin 1, angiotensin II receptor, Fbxw7-as1 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dear often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- angiotensin type II receptor
- endothelin receptor
- growth factor binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane