Slc22a19 Gene Summary [Mouse]
Enables organic anion transmembrane transporter activity and toxin transmembrane transporter activity. Acts upstream of or within organic anion transport. Predicted to be located in basolateral plasma membrane. Is expressed in metanephros. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to several human genes including SLC22A25 (solute carrier family 22 member 25). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc22a19 |
| Official Name | solute carrier family 22 (organic anion transporter), member 19 [Source:MGI Symbol;Acc:MGI:2442751] |
| Ensembl ID | ENSMUSG00000024757 |
| Bio databases IDs | |
| Aliases | solute carrier family 22 (organic anion transporter), member 19 |
| Synonyms | D630043A20Rik, OAT-5, rOat5, Slc22a10, Slc22a24, Slc22a9, solute carrier family 22, member 19, solute carrier family 22 (organic anion transporter), member 19 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc22a19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphoglycerate transporter family protein
- benzoate transport
- Sugar (and other) transporter
- short-chain fatty acid uptake transporter
- Multidrug resistance protein
- Major Facilitator Superfamily
- sodium-independent organic anion transporter
- phosphate:H+ symporter
- toxin transporter
- organic anion transporter
- cation transport protein
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- apical membrane
- basolateral membrane
- podocyte slit diaphragm