Abcc12 Gene Summary [Mouse]
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in mitochondrion. Is expressed in several structures, including genitourinary system; immune system; liver; musculature; and stomach. Orthologous to human ABCC12 (ATP binding cassette subfamily C member 12). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Abcc12 |
| Official Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 12 [Source:MGI Symbol;Acc:MGI:2441679] |
| Ensembl ID | ENSMUSG00000036872 |
| Bio databases IDs | |
| Aliases | ATP-binding cassette, sub-family C (CFTR/MRP), member 12 |
| Synonyms | 4930467B22Rik, ATP-binding cassette, sub-family C member 12, MRP9 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abcc12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid A export permease/ATP-binding protein MsbA
- heme ABC exporter, ATP-binding protein CcmA
- ABC transporter transmembrane region
- Six-transmembrane helical domain of the ATP-binding cassette transporters
- thiol reductant ABC exporter, CydD subunit
- cystic fibrosis transmembrane conductor regulator (CFTR)
- thiol reductant ABC exporter, CydC subunit
- multi drug resistance-associated protein (MRP)
- nickel import ATP-binding protein NikE
- ABC transporter
- thiamine ABC transporter, ATP-binding protein
- ABC transporter, permease/ATP-binding protein
- P-loop containing Nucleoside Triphosphate Hydrolases
- ATPases associated with a variety of cellular activities
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- phenobarbital
- diethylnitrosamine
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum