Btbd3 Gene Summary [Rat]

Predicted to enable identical protein binding activity. Predicted to be involved in cerebral cortex development and dendrite morphogenesis. Predicted to be located in nucleus. Predicted to be active in cytosol. Orthologous to human BTBD3 (BTB domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Btbd3
Official Name
BTB domain containing 3 [Source:RGD Symbol;Acc:1311623]
Ensembl ID
ENSRNOG00000008088
Bio databases IDs NCBI: 311462 Ensembl: ENSRNOG00000008088
Aliases BTB domain containing 3
Synonyms BTB domain containing 3, dJ742J24.1, mKIAA0952
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Btbd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • BTB And C-terminal Kelch
  • Broad-Complex, Tramtrack and Bric a brac
  • PHR domain
  • BTB_POZ
  • BTB/POZ domain
  • protein binding
  • BACK (BTB and C-terminal Kelch) domain
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • endometriosis
  • X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
regulated by
  • TNF
  • VEGF
  • TAL1
  • HeLa cells
  • levodopa
  • MIRN133A
role in cell
  • morphogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Btbd3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neurogenesis
  • cerebral cortex development
  • dendrite morphogenesis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.