Btbd3 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Involved in cerebral cortex development and dendrite morphogenesis. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and paravertebral ganglion. Orthologous to human BTBD3 (BTB domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Btbd3
Official Name
BTB (POZ) domain containing 3 [Source:MGI Symbol;Acc:MGI:2385155]
Ensembl ID
ENSMUSG00000062098
Bio databases IDs NCBI: 228662 Ensembl: ENSMUSG00000062098
Aliases BTB (POZ) domain containing 3
Synonyms BTB domain containing 3, dJ742J24.1, mKIAA0952
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Btbd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • BTB And C-terminal Kelch
  • Broad-Complex, Tramtrack and Bric a brac
  • PHR domain
  • BTB_POZ
  • BTB/POZ domain
  • protein binding
  • BACK (BTB and C-terminal Kelch) domain
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • endometriosis
  • X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
regulated by
  • TNF
  • VEGF
  • TAL1
  • HeLa cells
  • levodopa
  • MIRN133A
role in cell
  • morphogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Btbd3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neurogenesis
  • cerebral cortex development
  • dendrite morphogenesis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.