Tubd1 Gene Summary [Rat]
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and positive regulation of smoothened signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and microtubule. Orthologous to human TUBD1 (tubulin delta 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tubd1 |
| Official Name | tubulin, delta 1 [Source:RGD Symbol;Acc:1311967] |
| Ensembl ID | ENSRNOG00000053309 |
| Bio databases IDs | |
| Aliases | tubulin, delta 1 |
| Synonyms | 4930550G19Rik, LOC100363487, TUBD, tubulin delta 1, tubulin, delta 1, tubulin δ 1, tubulin, δ 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tubd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tubulin protein family of FtsZ and CetZ-like
- Tubulin/FtsZ family, GTPase domain
- protein binding
Pathways
Biological processes and signaling networks where the Tubd1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- anorexia
- cardiovascular disorder
- infection
- chronic kidney disease
- heart disease
- premenopausal breast cancer
- non-squamous lung carcinoma
- precursor B-cell acute lymphoblastic leukemia
- advanced large cell lung carcinoma
role in cell
- cohesion in
- cohesion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- centrosome
- centriole
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tubd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell projection organization
- positive regulation of smoothened signaling pathway
- microtubule cytoskeleton organization
- mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- centriole
- cytoplasm
- cilium
- cytosol
- nucleoplasm
- microtubule
Molecular Function
What the gene product does at the molecular level
- GTP binding
- structural constituent of cytoskeleton