Details
| Type | Mitochondrial Transfer RNA |
| Official Symbol | MT-TK |
| Official Name | mitochondrially encoded tRNA-Lys (AAA/G) [Source:HGNC Symbol;Acc:HGNC:7489] |
| Ensembl ID | ENSG00000210156 |
| Bio databases IDs | |
| Aliases | mitochondrially encoded tRNA-Lys (AAA/G) |
| Synonyms | mitochondrial tRNA Lys, mt-Tk-201, tRNA-Lys, TRNK |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MT-TK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- triplet codon-amino acid adaptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- myoclonus epilepsy and ragged red fibers syndrome
- Leigh syndrome
- MELAS syndrome
- mitochondrial Parkinson disease
- cardiomyopathy and deafness
- mitochondrial disorder
- progressive external ophthalmoplegia with myoclonus
- maternally transmitted diabetes-deafness syndrome
- complicated hereditary spastic paraplegia
- mitochondrial DNA depletion syndrome 1 (MNGIE type)
regulated by
regulates
- reactive oxygen species
- oxygen
role in cell
- consumption in
- phagocytosis
- production in
- quantity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria