Adgrf2 Gene Summary [Mouse]
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in heart; lung; metanephros; skin; and spleen. Orthologous to human ADGRF2P (adhesion G protein-coupled receptor F2, pseudogene). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adgrf2 |
| Official Name | adhesion G protein-coupled receptor F2 [Source:MGI Symbol;Acc:MGI:2182728] |
| Ensembl ID | ENSMUSG00000057899 |
| Bio databases IDs | |
| Aliases | adhesion G protein-coupled receptor F2 |
| Synonyms | adhesion G protein-coupled receptor F2, Gpr111, Gpr115, PGR20 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adgrf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 7 transmembrane receptor (Secretin family)
- GPCR proteolysis site, GPS, motif
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Adgrf2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- carbon
- KLK4
role in cell
- expression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown