Ugt1a2 Gene Summary [Mouse]
Predicted to enable several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to several human genes including UGT1A5 (UDP glucuronosyltransferase family 1 member A5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ugt1a2 |
| Official Name | UDP glucuronosyltransferase 1 family, polypeptide A2 [Source:MGI Symbol;Acc:MGI:3576049] |
| Ensembl ID | ENSMUSG00000090171 |
| Bio databases IDs | |
| Aliases | UDP glucuronosyltransferase 1 family, polypeptide A2 |
| Synonyms | 3-methylcholanthrene-inducible udp-glucuronosyltransferase, Bilirubin Udp-Glucuronosyltransferase Isoenzyme 1, UDP Glucoronosyltransferase, UDP glucuronosyltransferase 1 family, polypeptide A2, UDP glucuronosyltransferase family 1 member A2, pseudogene, Udpgt, Udpgt1, UDPGT 1-2, Ugt1, Ugt1a2, UGT1BP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ugt1a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glycosyltransferase family 1 and related proteins with GTB topology
- binding protein
- glycosyltransferase, MGT family
- enzyme binding
- protein homodimerization
- enzyme
- retinoid binding
- UDP-glucoronosyl and UDP-glucosyl transferase
- protein heterodimerization
- glucuronosyltransferase
Pathways
Biological processes and signaling networks where the Ugt1a2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- microsome