B3gnt6 Gene Summary [Rat]
Predicted to enable UDP-glycosyltransferase activity and galactosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Orthologous to human B3GNT6 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | B3gnt6 |
| Official Name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Source:RGD Symbol;Acc:1310926] |
| Ensembl ID | ENSRNOG00000014471 |
| Bio databases IDs | |
| Aliases | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
| Synonyms | beta-1,3-Gn-T6, beta3Gn-T6, BGnT-6, C3gnt, Core-3, RGD1310926, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, UDP-GlcNAc:betaGal β-1,3-N-acetylglucosaminyltransferase 6, β-1,3-Gn-T6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat B3gnt6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
- galactosyltransferase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- tumorigenesis
- early-onset schizophrenia
- experimental colitis
- overall survival
regulated by
- KMT2D
- zinc chloride
- D-glucose
- triamcinolone acetonide
regulates
- O-glycan
- MUC2
- core 3 O-glycan
role in cell
- activity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi region
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat B3gnt6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycoprotein biosynthetic process
- protein O-linked glycosylation
- O-glycan processing
- poly-N-acetyllactosamine biosynthetic process
- O-glycan processing, core 3
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- UDP-glycosyltransferase activity
- acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity
- beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
- galactosyltransferase activity