Gja10 Gene Summary [Rat]

Predicted to enable gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to act upstream of or within detection of light stimulus involved in visual perception; gamete generation; and synapse assembly. Predicted to be located in gap junction. Predicted to be part of connexin complex. Orthologous to human GJA10 (gap junction protein alpha 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gja10
Official Name
gap junction protein, alpha 10 [Source:RGD Symbol;Acc:1309630]
Ensembl ID
ENSRNOG00000006478
Bio databases IDs NCBI: 313126 Ensembl: ENSRNOG00000006478
Aliases gap junction protein, alpha 10
Synonyms Cx-57, Cx59, CX62, Cxnn, gap junction protein alpha 10, gap junction protein, alpha 10, gap junction protein α 10, gap junction protein, α 10, RGD1309630
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gja10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Connexin homologues
  • Gap junction channel protein cysteine-rich domain
  • transporter
  • Connexin
  • gap-junction forming channel

Pathways

Biological processes and signaling networks where the Gja10 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
regulates
role in cell
  • generation
  • phosphorylation in
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • gap junctions

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gja10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • detection of light stimulus involved in visual perception
  • synapse assembly
  • transmembrane transport
  • cell-cell signaling
  • gamete generation

Cellular Component

Where in the cell the gene product is active
  • connexon complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • gap junction channel activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.