Gja10 Gene Summary [Mouse]
Enables gap junction channel activity. Acts upstream of or within detection of light stimulus involved in visual perception; gamete generation; and synapse assembly. Located in gap junction. Is expressed in several structures, including eye; gonad; intestine; liver; and sciatic nerve. Orthologous to human GJA10 (gap junction protein alpha 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gja10 |
| Official Name | gap junction protein, alpha 10 [Source:MGI Symbol;Acc:MGI:1339969] |
| Ensembl ID | ENSMUSG00000051056 |
| Bio databases IDs | |
| Aliases | gap junction protein, alpha 10 |
| Synonyms | Cx-57, Cx59, CX62, Cxnn, gap junction protein alpha 10, gap junction protein, alpha 10, gap junction protein α 10, gap junction protein, α 10, RGD1309630 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gja10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Connexin homologues
- Gap junction channel protein cysteine-rich domain
- transporter
- Connexin
- gap-junction forming channel
Pathways
Biological processes and signaling networks where the Gja10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- gap junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gja10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- detection of light stimulus involved in visual perception
- synapse assembly
- transmembrane transport
- cell-cell signaling
- gamete generation
Cellular Component
Where in the cell the gene product is active
- connexon complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- gap junction channel activity