Scd4 Gene Summary [Rat]
Predicted to enable iron ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Predicted to be involved in cellular response to nutrient; fatty acid biosynthetic process; and response to fatty acid. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Scd4 |
| Official Name | stearoyl-coenzyme A desaturase 4 [Source:RGD Symbol;Acc:1563648] |
| Ensembl ID | ENSRNOG00000032554 |
| Bio databases IDs | |
| Aliases | stearoyl-coenzyme A desaturase 4 |
| Synonyms | ACOD4, RGD1563648, stearoyl-coenzyme A desaturase 4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Scd4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- stearoyl-CoA 9-desaturase
- Membrane-FADS-like
- oxidoreductase
- Fatty acid desaturase
- CoA desaturase
- iron ion binding
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- hypercholesterolemia
- hyperinsulinism
role in cell
- expression in
- growth
- accumulation
- accumulation in
- response by
- enlargement
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- nucleoli