Idi2 Gene Summary [Mouse]
Predicted to enable isopentenyl-diphosphate delta-isomerase activity. Acts upstream of or within negative regulation of cholesterol biosynthetic process. Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Orthologous to human IDI2 (isopentenyl-diphosphate delta isomerase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Idi2 |
| Official Name | isopentenyl-diphosphate delta isomerase 2 [Source:MGI Symbol;Acc:MGI:2444315] |
| Ensembl ID | ENSMUSG00000033520 |
| Bio databases IDs | |
| Aliases | isopentenyl-diphosphate delta isomerase 2 |
| Synonyms | 4833405L16Rik, IPPI2, isopentenyl-diphosphate delta isomerase 2, isopentenyl-diphosphate δ isomerase 2, RGD1559783, RGD1562352 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Idi2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- isopentenyl-diphosphate delta-isomerase, type 1
- NUDIX domain
- isopentenyl-diphosphate D-isomerase
- enzyme
- NUDIX hydrolase superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
- cholesterol
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- peroxisomes