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GeneGlobe ID: PAHS-3401Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT

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Product Specification

RT2 Profiler PCR Array

Target List

Apoptosis
ABL1AKT1APAF1BADBAK1BAXBCL2BCL2L1BCL2L1BCL2L1BCL2L11BIDBIRC3CASP1CASP3CASP7CASP8CASP9CD40CD40LGCFLARFADDFASFASLGGADD45AMCL1TNFTNFRSF10ATNFRSF10BTNFRSF1ATNFSF10TP53XIAP
Necrosis
ATP6V1G2BMFCCDC103CD300LDCLEC18ACOMMD4CYLDDEFB1DPYSL4EIF5BFOXI1GALNT5GRB2HOXA3HSPBAP1JPH3KCNIP1MAGNUDT13OR10J3PARP2PVRRAB25S100A7ASPATA2SYCP2MACO1TNFAIP8L1TNFRSF1ATXNL4B
DNA Damage & Repair
APEX1ATMATRBRCA1BRCA2CDKN1ACHEK1CHEK2DDIT3ERCC1ERCC2ERCC3ERCC5ERCC6GADD45ALIG4MDM2MGMTMLH1MSH2OGG1PARP1PCNAPRKDCRAD51TP53XPAXPCXRCC1XRCC5
Mitochondrial Energy Metabolism
ACLYACO1ACO2COX6B1COX8ACSCYC1DLDDLSTFHIDH1IDH2IDH3AIDH3BIDH3GMDH1MDH1BMDH2OGDHSDHASDHBSDHCSDHDSUCLA2SUCLG1SUCLG2UCP1UCP2UCP3
Fatty Acid Metabolism
ACAA1ACAA2ACAD11ACAD9ACADLACADMACADSACADSBACADVLACAT1ACAT2ACOT1ACOT12ACOT6ACOT7ACOT8ACOT9ACOX1ACOX2ACOX3BDH2CPT1ACPT1BCPT2CRATCROTDECR1ECHS1EHHADHGCDHHADHA
Oxidative Stress & Antioxidant Response
AASSCATCTSBDHCR24DUOX1DUOX2EPXGPX1GPX2GPX3GPX4GPX5GPX6GPX7IDH1MPONQO1NUDT1NUDT15PPP1R15BPRDX1PRDX2PRDX6SOD1TPOTXNIPTXNRD2UCP3
Heat Shock Response
CRYAACRYABDNAJA1DNAJA2DNAJA3DNAJB1DNAJB6DNAJC3DNAJC5DNAJC6HSF1HSF2HSP90AA1HSP90AB1HSP90B1HSPA1AHSPA1BHSPA1LHSPA2HSPA4HSPA5HSPA8HSPA9HSPB1HSPB2HSPB6HSPB8HSPD1HSPE1HSPH1TCP1
Endoplasmic Reticulum Stress & Unfolded Protein Response
AMFRATF4ATF6BAXDDIT3DERL1EDEM1EDEM3EIF2AK3ERN2ERO1AERO1BFBXO6GADD45AHERPUD1HTRA2HTRA4MBTPS1MBTPS2NPLOC4NUCB1OS9PFDN5SEC62SEL1LSELENOSSERP1SYVN1UBE2G2UBE2J2UBXN4VCPXBP1
Cytochrome P450s & Phase I Drug Metabolism
CYP1A1CYP1A2CYP2B6CYP2C19CYP2C9CYP2D6CYP2E1CYP3A4ESDFMO2FMO3FMO4FMO5MAOAMAOB
Steatosis
ACACAADKALDH2AQP4CD36COMTCYP2E1CYP7B1DNM1ENO1FASFASNGPD1HAAOHADHBKHKLMNALPLLY6DMAPK8MTTPPCCAPNPLA3PPARARETNSCDSREBF1SYT1TFF3VCP
Cholestasis
ABCB1ABCB4ABCC1ABCC2ABCC3APOEATP8B1CYP3A4CYP7A1DLATESR1HLA-DRB1ICAM1IL10IL1BIL2IL6JAG1MPONR1H4NUP210SLC51ASLC51BPDYNRDXSLC10A1TGFB1TNF
Phospholipidosis
ABCB1ALDH1A1ASAH1ASNSCES2CTSBEPHX1FABP1TIMM10BGSTM4HPNINHBELSSMANBAMLXMRPS18BNR0B2PORS100A8MSMO1SERPINA3SLC2A3SLCO1A2SMPD1STBD1TAGLNUGT1A1UGT2A1UGT2B4WIPI1
Immunotoxicity
ADH1CAHRAHSGALBAPOA5APOFC3C9CASP3CD19CD4CD44CD80CD86CD8ACTSECYP1A1CYP3A4EP300F2FABP1FASGPTGSTA3HPXHRGHSPA5IFNA1IFNGIL10IL13IL1AIL1BIL2IL4IL5IL6ITGAXKLF1LYZMETAP2MKI67NFKB1NR5A2PON1POU3F3PTGS2PTPRCSOD1TNFTRIM10UBQLN2

Product Resources

icon_0041_download-s Download Target List
icon_0245_cc_gen_pdf-s Gene Table for 384-well Array
File Size: 185.27 KBLanguage: English

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Resources

Supplementary Protocols (10)
Brochures & Guides (3)
RT2 Profiler PCR Arrays: Pathway Analysis - (EN)
PDF (1MB)
Total RNA Discovery - (EN)
PDF (255KB)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Technical Guide to QIAGEN PCR Arrays
PDF (2MB)
Safety Data Sheets (1)
Safety Data Sheets
Articles (17)
(EN) Control of PPARγ and mTOR in insulin resistance
(EN) miRNA regulation of angiogenesis: new roles for IGF-1R signaling and heparin
(EN) Regulation of BAX mediated apoptosis by BCL2 family members
(EN) Chemokines: manipulators of metastasis
(EN) DNA damage repair — regulation through autophagy
(EN) Silencing cell-cell communication to combat drug toxicity
(EN) Cellular stress, TGF-β, and EMT: what are the true origins of fibrosis?
(EN) The role of inflammation in cancer
(EN) What enhances the inflammatory response: new players and unexpected roles
(EN) Induced pluripotent stem cells: real stem cells?
(EN) Lipid autophagy in obesity and atherosclerosis: chewing the fat
(EN)Metabolic homeostasis: regulation of FOXO by class IIa HDACs
(EN)Regulation of the extracellular matrix by miRNA: impact on cancer metastases
(EN)Inflammation and neurodegenerative disease: a role for the estrogen receptor in suppression of inflammation in the brain
(EN)A good transcription factor gone rogue: the two faces of NRF2 in oxidative stress
(EN)Managing mortality: how cells regulate telomerase activity
(EN) Master Regulators Direct TGF-beta and Smad Signaling in Different Cell Types
Download Files (3)
Housekeeping Gene Data Analysis
XLSX (60KB)
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

RT2 Profiler PCR Array Data Analysis v3.5 Handbook
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