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Positive results with as little as 25 ng RNA.
High reproducibility among different users.
PCR arrays yield highly accurate results.
A single gene-specific product in every reaction.
Simple procedure.

RT² Profiler™ PCR Array Dog Cellular Senescence

GeneGlobe ID: PAFD-050Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

Product Specification

RT2 Profiler PCR Array

Target List

Senescence Pathway
ATMBMI1CCND1CCNE1CDK2CDK4CDK6CDKN1ACDKN2ACDKN2DCHEK1CHEK2E2F1E2F3ETS1ETS2MDM2RB1RBL2TP53TWIST1
Senescence Initiators
p53 Signaling
ABL1
p53 / pRb Signaling & the Cell Cycle
AKT1CCNA1CCNA2CCNB1CDC25BCDC25CCDKN2BCDKN2CCREG1GSK3BID1IGF1RIGFBP3ING1MAP2K6MAPK11MAPK14MORC3MYCPCNAPIK3CAPLAURBL1SERPINB2SERPINE1SIRT1SMAD3SPARCTGFB1
Interferon Signaling
CDKN1ACDKN1BEGR1IFNGIGFBP3IGFBP7IRF3IRF5IRF7NFKB1RB1SERPINB2
Insulin Growth Factor (IGF) Related
IGF1IGF1RIGFBP3IGFBP5IGFBP7
MAP Kinase Signaling
CDC25BHRASMAP2K1MAP2K3MAP2K6MAPK11MAPK14
Oxidative Stress
HRASMAPK14NOX4PRKCDSOD1SOD2
DNA Damage & Repair
ATMGADD45APCNATERF2TP53BP1
Senescence Responses
p53 Effectors
E2F1HRASIGFBP3MYC
p21 Effectors
CALR
p16 Effectors
TBX2TBX3
Cytoskeleton Regulators
AKT1FN1GSNHRASPIK3CAPLAUSERPINE1SPARCTHBS1VIM
Cell Adhesion Molecules
CD44COL1A1COL3A1TGFB1TGFB1I1THBS1
Other Senescence Response Genes
GLB1PTEN

Product Resources

icon_0041_download-s Save Target List
icon_0245_cc_gen_pdf-s Array Layout for PCR Plates
File Size: 140.43 KBLanguage: English
icon_0245_cc_gen_pdf-s Array Layout for Rotor-Gene Q
File Size: 134.9 KBLanguage: English

Resources

Supplementary Protocols (10)
Bio-Rad CFX96 and CFX384 instrument setup instructions for RT2 Profiler PCR Arrays
PDF (298KB)
Roche LightCycler 480 real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (1MB)
Eppendorf Mastercycler ep realplex instrument setup instructions for RT2 Profiler PCR Arrays
PDF (554KB)
ABI 7900HT (for SDS Software 2.1, 2.3 and 2.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (320KB)
Stratagene Mx3000P qPCR System real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (259KB)
Rotor-Gene Q real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (175KB)
ABI 7500 & ABI 7500 FAST (Software Version 2.0.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (388KB)
Bio-Rad iCycler & iQ Real-Time PCR Systems (for Software Version 3.1) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (249KB)
ABI StepOnePlus (for Software Version 2.0) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (77KB)
Life Technologies ViiA7 (ViiA 7 Software v1.2) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (511KB)
Brochures & Guides (3)
Technical Guide to QIAGEN PCR Arrays
PDF (2MB)
RT2 Profiler PCR Arrays: Pathway Analysis - (EN)
PDF (1MB)
Total RNA Discovery - (EN)
HTML (255KB)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Safety Data Sheets (1)
Safety Data Sheets
Articles (17)
(EN)Managing mortality: how cells regulate telomerase activity
(EN) The role of inflammation in cancer
(EN)A good transcription factor gone rogue: the two faces of NRF2 in oxidative stress
(EN)Metabolic homeostasis: regulation of FOXO by class IIa HDACs
(EN) Chemokines: manipulators of metastasis
(EN) Cellular stress, TGF-β, and EMT: what are the true origins of fibrosis?
(EN) Regulation of BAX mediated apoptosis by BCL2 family members
(EN)Inflammation and neurodegenerative disease: a role for the estrogen receptor in suppression of inflammation in the brain
(EN) Control of PPARγ and mTOR in insulin resistance
(EN) What enhances the inflammatory response: new players and unexpected roles
(EN) DNA damage repair — regulation through autophagy
(EN) Lipid autophagy in obesity and atherosclerosis: chewing the fat
(EN) Induced pluripotent stem cells: real stem cells?
(EN) Silencing cell-cell communication to combat drug toxicity
(EN) miRNA regulation of angiogenesis: new roles for IGF-1R signaling and heparin
(EN) Master Regulators Direct TGF-beta and Smad Signaling in Different Cell Types
(EN)Regulation of the extracellular matrix by miRNA: impact on cancer metastases
Download Files (3)
RT2 Profiler PCR Array Data Analysis v3.5 Handbook
PDF (770KB)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Housekeeping Gene Data Analysis
XLSX (60KB)
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Explore the RNA Universe!
PDF (1MB)
Poster for download
Kit Handbooks (1)
RT2 Profiler PCR Array Handbook
PDF (702KB)
For pathway-focused gene expression profiling using real-time RT-PCR
Performance Data (7)
RT2 Profiler Housekeeping Genes PCR Array Data Analysis 1808
XLSX (65KB)
PCR_Array_4x96_384-Well_Conversion Spreadsheet
XLSX (38KB)
RT2 Profiler PCR Array Data Analysis Spreadsheet 1904
XLSX (3MB)
RT2 Profiler RNA QC PCR Array Data Analysis Spreadsheet 1808
XLSX (60KB)
Universal Custom PCR Array Conversion
XLSX (291KB)
RT2 qPCR Assay Data Analysis 1808 Spreadsheet
XLSX (104KB)
RT2 Profiler PCR Array 384HT Data Analysis Spreadsheet 1808
XLSX (1MB)
Instrument Technical Documents (2)
QIAGEN Service Core - (EN)
PDF (333KB)
For gene expression and genomic analysis
(EN) - RT2 Profiler PCR Arrays
PDF (431KB)
For pathway-focused gene expression analysis
White Papers (2)
RT2 Profiler PCR Arrays: Pathway-focused gene expression profiling with qRT-PCR
PDF (1MB)
RT2 Profiler PCR Array application examples
PDF (563KB)
Gene Expression Analysis (1)
(EN) Wnt Signaling: GSK3 Inhibition Through Sequestration in Multivesicular Bodies
Certificates of Analysis (1)
Certificates of Analysis
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Introducing the RT² Profiler™ PCR Array Dog Cellular Senescence, a cutting-edge addition to our RT2 Profiler PCR Arrays lineup, specifically designed for RNA expression applications. This premium product offers unparalleled performance for researchers working with Dog models. Leveraging advanced technology, the RT² Profiler™ PCR Array Dog Cellular Senescence facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting RNA expression, or any other sophisticated analyses, this product from our RT2 Profiler PCR Arrays collection ensures optimal efficiency and reproducibility for Dog studies. Embrace the future of research with RT² Profiler™ PCR Array Dog Cellular Senescence and elevate your work to new heights.
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