GTDC1 Gene Summary [Human]

Predicted to enable glycosyltransferase activity. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GTDC1
Official Name
glycosyltransferase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20887]
Ensembl ID
ENSG00000121964
Bio databases IDs NCBI: 79712 Ensembl: ENSG00000121964
Aliases glycosyltransferase like domain containing 1, mannosyltransferase-like
Synonyms E330008O22Rik, FLJ11753, glycosyltransferase-like domain containing 1, Hmat-Xa, mat-Xa, QTMAN
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GTDC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF3524)
  • enzyme
  • tRNA-queuosine beta-mannosyltransferase
  • Glycosyl transferases group 1

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • multiple sclerosis
  • mouth mucosal ulcer
regulated by
role in cell
  • translation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GTDC1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translation
  • tRNA modification

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • tRNA-queuosine beta-mannosyltransferase activity

Gene-Specific Assays for Results You Can Trust

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