Cyp2j9 Gene Summary [Mouse]

Predicted to enable heme binding activity; isomerase activity; and monooxygenase activity. Predicted to be involved in epoxygenase P450 pathway; linoleic acid metabolic process; and xenobiotic metabolic process. Located in endoplasmic reticulum. Is expressed in alimentary system; ductus arteriosus; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cyp2j9
Official Name
cytochrome P450, family 2, subfamily j, polypeptide 9 [Source:MGI Symbol;Acc:MGI:1921769]
Ensembl ID
ENSMUSG00000015224
Bio databases IDs NCBI: 74519 Ensembl: ENSMUSG00000015224
Aliases cytochrome P450, family 2, subfamily j, polypeptide 9
Synonyms 8430417E17Rik, Cyp2j3, cytochrome P450, family 2, subfamily j, polypeptide 3, Cytochrome P450, family 2, subfamily j, polypeptide 9
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cyp2j9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytochrome P450 (CYP) superfamily
  • Cytochrome P450
  • arachidonic acid 11,12-epoxygenase
  • arachidonic acid 14,15-epoxygenase
  • monooxygenase
  • isomerase
  • enzyme
  • paired donor oxygen oxidoreductase
  • arachidonic acid epoxygenase

Pathways

Biological processes and signaling networks where the Cyp2j9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • AKT
  • insulin
  • ACAC
  • AMPK
  • D-glucose
  • ADIPOQ
  • epoxyeicosatrienoic acid
regulated by
  • fluconazole
  • valproic acid
  • triadimefon
  • propiconazole
  • myclobutanil
role in cell
  • expression in
  • endoplasmic reticulum stress response

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cell periphery
  • Endoplasmic Reticulum
  • endoplasmic reticulum membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.