Mrgprb4 Gene Summary [Mouse]
Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion. Orthologous to human MRGPRX2 (MAS related GPR family member X2); MRGPRX3 (MAS related GPR family member X3); and MRGPRX4 (MAS related GPR family member X4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrgprb4 |
| Official Name | MAS-related GPR, member B4 [Source:MGI Symbol;Acc:MGI:3033119] |
| Ensembl ID | ENSMUSG00000070550 |
| Bio databases IDs | |
| Aliases | MAS-related GPR, member B4 |
| Synonyms | MAS-related GPR, member B4, MAS-related GPR, member B5, MAS-related G protein-coupled receptor, member B5, Mgrg11, MrgB4, MrgB5, Mrgprb4, Mrgprb5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrgprb4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- neuropeptide binding
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
- transmembrane receptor
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane