Kbtbd6 Gene Summary [Mouse]
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; and regulation of Rac protein signal transduction. Predicted to be located in nucleus. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KBTBD7 (kelch repeat and BTB domain containing 7). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kbtbd6 |
| Official Name | kelch repeat and BTB (POZ) domain containing 6 [Source:MGI Symbol;Acc:MGI:3643058] |
| Ensembl ID | ENSMUSG00000075502 |
| Bio databases IDs | |
| Aliases | kelch repeat and BTB (POZ) domain containing 6 |
| Synonyms | EG432879, Gm5465, kelch repeat and BTB domain containing 6, kelch repeat and BTB (POZ) domain containing 6, Zbtbd6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kbtbd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kelch motif
- BTB And C-terminal Kelch
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- BTB/POZ domain
- BACK (BTB and C-terminal Kelch) domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus