Target List
Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build
Leukemia
Acute Lymphoblastic Leukemia (ALL)
ABL1ABL2 (ARG)BIRC3 (c-IAP2)BRAFBTKCDKN2A (P16INK4A)CDKN2B (p15INK4b)CREBBP (CBP)CRLF2 (TSLPR)EBF1EP300ETV6FBXW7FLT3GATA3HRASIKZF1IL7RJAK1JAK2JAK3KDM6AKMT2AKRASMYCNOTCH1NRASPAX5PDGFRBPLCG2PTENPTPN11RUNX1 (AML1)SF3B1SH2B3TP53 (p53)
Acute Myeloid Leukemia (AML)
ANKRD26ASXL1ATRXBRCA1BRCA2CBFBCBLBCBLCCCND2CDC25CCEBPACUX1DCKDDX41DHX15DNMT3AELANEETV6FLT3GATA1GATA2GNASHRASIDH1IDH2IKZF1IKZF2IKZF3JAK2KDM6AKIT (CD117)KMT2AKRASLUC7L2MTORNPM1NRASNUP214PDGFRAPICALMPRPF8PTPN11RB1RBBP6RPS14RUNX1 (AML1)SF3B1SLC29A1SMC1ATERTTET1TET2TP53 (p53)U2AF1U2AF2WT1ZEB2
Acute Promyelocytic Leukemia (APML; APL)
CEBPANPM1NUMA1RARARUNX1 (AML1)
Atypical Chronic Myeloid Leukemia (aCML)
ASXL1CBLCEBPAEZH2FLT3JAK2KRASNPM1NRASRUNX1 (AML1)SETBP1SRSF2TET2U2AF1
Chronic Lymphocytic Leukemia (CLL)
ATRXBCL2BIRC3 (c-IAP2)BRAFCBLBCCND2CD38CUX1GNASGNB1LUC7L2MYD88NOTCH1NRASPTPN11SF3B1TP53 (p53)U2AF2XPO1ZAP70
Chronic Myeloid Leukemia (CML)
ABL1ASXL1BCORBCRBRAFCBLCREBBP (CBP)DNMT3ADNMT3BEZH2IDH1IDH2IKZF1JAK2KRASNPM1NRASRUNX1 (AML1)TET1TET2TP53 (p53)WT1
Chronic Myelomonocytic Leukemia (CMML)
ASXL1BCORBCORL1CBLCEBPADNMT3AEZH2FLT3IDH1IDH2JAK2KIT (CD117)KRASMPLNF1NPM1NRASPHF6PTPN11RUNX1 (AML1)SETBP1SF3B1SRSF2STAG2TET2TP53 (p53)U2AF1ZRSR2
Hairy Cell Leukemia
BRAFCDKN1B (P27KIP1)MAP2K1TP53 (p53)
Juvenile Myelomonocytic Leukemia
ARHGAP26CBLKRASNRASPTPN11
Lymphomas
Acute Lymphocytic Lymphomas
BIRC3 (c-IAP2)BTKCDKN2A (P16INK4A)CDKN2B (p15INK4b)MYCNOTCH1PLCG2SF3B1TP53 (p53)
B Cell Lymphomas
BCL6BRAFCD79ACHEK2 (RAD53)EZH2MAP2K1MYD88STAT6TNFRSF14TP53 (p53)
Burkitt Lymphomas
CBLBGNA13H1-4MTORMYC
Diffuse Large B Cell Lymphomas
B2MBCL2CBLBGNA13H1-4KMT2DMTORPIM1PRPF8SOCS1TNFAIP3
Follicular Lymphomas
ARID1ABCL10BCL2CARD11CREBBP (CBP)EP300EZH2FOXO1KMT2DMEF2B
Mantle Cell Lymphomas
ATMCCND1
Marginal Zone Lymphomas
KLF2MYD88NOTCH2TNFAIP3TP53 (p53)
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas
BCL10TNFAIP3
Non-Hodgkin Lymphomas
BRAFCASP10 (MCH4)NRASPIK3CA (p110-alpha)RAD54BRAD54LTP53 (p53)
Primary Cutaneous Lymphomas
CD79BMYD88
Small Lymphocytic Lymphomas
ATRXBCL2CBLBCCND2CUX1GNASLUC7L2U2AF2XPO1
T Cell Lymphomas
ARID1BATMCBLBCCR4DNMT3AIDH1IDH2INO80JAK1JAK3RHOASETD2STAT3STAT5BTET2
Myelodysplastic Syndromes & Myeloproliferative Neoplasms
Myelodysplastic Syndromes
ANKRD26ASXL1ATRXBCORBCORL1CALRCBLCEBPACSF3R (GM-CSFR)CUX1DDX41DKC1DNMT3AETNK1ETV6EZH2FLT3GATA2GNASGNB1IDH1IDH2JAK2JAK3KIT (CD117)KRASMPLNF1NPM1NRASPHF6PIGAPPM1DPTPN11RAD21RUNX1 (AML1)SAMD9SAMD9LSETBP1SF3B1SMC3SRP72SRSF2STAG2STAT3TERCTERTTET2TP53 (p53)U2AF1WT1ZRSR2
Myeloproliferative Neoplasms
ASXL1BCORCALRCBLCSF3R (GM-CSFR)DNMT3AETV6EZH2IDH1IDH2JAK2KIT (CD117)MPLNOTCH1NRASPDGFRARUNX1 (AML1)SETBP1SF3B1SH2B3SRSF2STAT3STAT5BTET2TP53 (p53)U2AF1ZRSR2
Other Myeloid Neoplasms
Essential Thrombocythemia
ASXL1CBLIDH2JAK2MPLSF3B1TET2TP53 (p53)
Multiple Myeloma
ATMBARD1BRAFBRCA1BRCA2BRIP1CHEK1CHEK2 (RAD53)CXCR4EGFR (ERBB1)ERBB2 (HER-2, NEU)FANCLFGFR3IDH1IDH2KIT (CD117)KRASMETNRASPALB2PDGFRARAD51BRAD51CRAD51DRETTP53 (p53)
Plasma Cell Myeloma
HRASMTORRB1SLC29A1
Polycythemia Vera
ASXL1DNMT3AEZH2IDH1JAK2NRASTET2TP53 (p53)
Primary Myelofibrosis
ASXL1CBLDNMT3AEZH2IDH1IDH2JAK2MPLNF1NRASSETBP1SF3B1SRSF2TET2TP53 (p53)
Systemic Mastocytosis
ASXL1CBLDNMT3AETV6EZH2IDH2JAK2KIT (CD117)KRASNPM1NRASRUNX1 (AML1)SETBP1SF3B1SRSF2TET2TPSAB1U2AF1
Waldenstrom Macroglobulinemia
CXCR4MYD88