H60b Gene Summary [Mouse]

Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within natural killer cell mediated cytotoxicity. Located in membrane. Orthologous to human RAET1E (retinoic acid early transcript 1E). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
H60b
Official Name
histocompatibility 60b [Source:MGI Symbol;Acc:MGI:3649078]
Ensembl ID
ENSMUSG00000075297
Bio databases IDs NCBI: 667281 Ensembl: ENSMUSG00000075297
Aliases histocompatibility 60b
Synonyms 4632413I24Rik, EG667281, Gm9491, H60b, H60bl1, H60c, histocompatibility 60b, histocompatibility 60b like 1, histocompatibility 60c
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse H60b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • extracellular domain
  • Class I Histocompatibility antigen, domains alpha 1 and 2
  • natural killer cell lectin-like receptor binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • activation
  • lysis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.