Ranbp3l Gene Summary [Mouse]
Enables SMAD binding activity. Involved in mesenchymal cell differentiation involved in bone development; negative regulation of osteoblast differentiation; and positive regulation of myoblast differentiation. Predicted to be located in cytoplasm and nucleus. Is expressed in meninges. Orthologous to human RANBP3L (RAN binding protein 3 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ranbp3l |
| Official Name | RAN binding protein 3-like [Source:MGI Symbol;Acc:MGI:2444654] |
| Ensembl ID | ENSMUSG00000048424 |
| Bio databases IDs | |
| Aliases | RAN binding protein 3-like |
| Synonyms | C130037N17Rik, LOC102551932, RAN binding protein 3-like, RGD1307559 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ranbp3l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SMAD binding
- protein binding
- Pleckstrin homology-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ranbp3l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of myoblast differentiation
- protein export from nucleus
- negative regulation of osteoblast differentiation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- protein binding
- SMAD binding
- GTPase activator activity