Sult1c3 Gene Summary [Rat]
Enables aryl sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; cholesterol metabolic process; and sulfation. Predicted to act upstream of or within sulfur compound metabolic process. Predicted to be active in cytoplasm. Orthologous to human SULT1C3 (sulfotransferase family 1C member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sult1c3 |
| Official Name | sulfotransferase family 1C member 3 [Source:RGD Symbol;Acc:3768] |
| Ensembl ID | ENSRNOG00000011269 |
| Bio databases IDs | |
| Aliases | sulfotransferase family 1C member 3 |
| Synonyms | HAST-I, LOC100910235, St1c1, ST1C3, Stp2, sulfotransferase family 1C member 3, sulphotransferase family 1C member 3, Sult1a2, Sult1c1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sult1c3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- bile-salt sulfotransferase
- Sulfotransferase domain
- alcohol sulfotransferase
- enzyme
- protein binding
- aryl sulfotransferase
- 3'-phosphoadenosine 5'-phosphosulfate binding
- Sulfotransferase family
Pathways
Biological processes and signaling networks where the Sult1c3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Sult1c3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid metabolic process
- xenobiotic metabolic process
- 3'-phosphoadenosine 5'-phosphosulfate metabolic process
- sulfation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- aryl sulfotransferase activity
- 3'-phosphoadenosine 5'-phosphosulfate binding
- alcohol sulfotransferase activity