TAS2R39 Gene Summary [Human]
The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015]
Details
| Type | Protein Coding |
| Official Symbol | TAS2R39 |
| Official Name | taste 2 receptor member 39 [Source:HGNC Symbol;Acc:HGNC:18886] |
| Ensembl ID | ENSG00000236398 |
| Bio databases IDs | |
| Aliases | taste 2 receptor member 39 |
| Synonyms | LOC684775, mt2r34, T2R39, T2R57, Tas2r139, taste 2 receptor member 39, taste receptor, type 2, member 139 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TAS2R39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- taste receptor
- Taste receptor protein (TAS2R)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the TAS2R39 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- denatonium benzoate
- PTBP3
regulated by
- denatonium benzoate
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TAS2R39 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- detection of chemical stimulus involved in sensory perception of bitter taste
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- bitter taste receptor activity