PTENP1 Gene Summary [Human]
PTENP1 represents a highly homologous processed pseudogene of PTEN (phosphatase and tensin homolog), a protein that encodes a tumor suppressor that functions by negatively regulating the AKT/PKB signaling pathway. PTENP1 is found on chromosome 9 and regulates PTEN by both sense and antisense RNAs (Gene ID: 101243555). This long-noncoding RNA (lncRNA) acts as a decoy for PTEN targeting microRNAs and also exerts a tumor suppressive activity. [provided by RefSeq, Jun 2020]
Details
| Type | Processed Transcript |
| Official Symbol | PTENP1 |
| Official Name | phosphatase and tensin homolog pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9589] |
| Ensembl ID | ENSG00000237984 |
| Bio databases IDs | |
| Aliases | phosphatase and tensin homolog pseudogene 1 |
| Synonyms | phosphatase and tensin homolog pseudogene 1, psiPTEN, PTEN2, PTENpg1, PTEN-rs, PTH2 |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm