PTENP1-AS Gene Summary [Human]
PTENP1-AS encodes an antisense RNA (asRNA) of PTENP1, a PTEN (phosphatase and tensin homolog) pseudogene. PTENP1 regulates PTEN by both sense (GeneID: 11191) and antisense RNAs. This antisense RNA (PTENP1-AS) regulates PTEN transcription and mRNA stability. [provided by RefSeq, Jun 2020]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | PTENP1-AS |
| Official Name | PTENP1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:48773] |
| Ensembl ID | ENSG00000281128 |
| Bio databases IDs | |
| Aliases | PTENP1 antisense RNA |
| Synonyms | PTENP1 antisense RNA, PTENpg1-asRNA |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PTENP1-AS often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- translation repressor
- mRNA binding
- protein binding activity, bridging
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PTENP1-AS gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of G1/S transition of mitotic cell cycle
- chromatin silencing by small RNA