Lipn Gene Summary [Mouse]

Predicted to enable sterol ester esterase activity and triacylglycerol lipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including brain; exocrine gland; gonad; hemolymphoid system gland; and respiratory system. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPN (lipase family member N). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Lipn
Official Name
lipase, family member N [Source:MGI Symbol;Acc:MGI:1917416]
Ensembl ID
ENSMUSG00000024770
Bio databases IDs NCBI: 70166 Ensembl: ENSMUSG00000024770
Aliases lipase, family member N
Synonyms 2210418G03Rik, lipase, family member N, Lipl4
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lipn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolase fold
  • alpha/beta hydrolases
  • Partial alpha/beta-hydrolase lipase region

Pathways

Biological processes and signaling networks where the Lipn gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • valproic acid
  • 4-aminosalicylate
phenotypes
  • decreased circulating glucose level
  • abnormal circulating glucose level

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.