Mosmo

Involved in negative regulation of smoothened signaling pathway; regulation of neuron differentiation; and regulation of protein stability. Acts upstream of or within several processes, including chordate embryonic development; embryonic limb morphogenesis; and smoothened signaling pathway. Located in Golgi apparatus and ciliary membrane. Is expressed in several structures, including central nervous system; eye; heart; liver; and lung. Orthologous to human MOSMO (modulator of smoothened). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mosmo often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mosmo gene, providing context for its role in the cell.