Mosmo Gene Summary [Rat]
Predicted to be involved in negative regulation of smoothened signaling pathway; regulation of neuron differentiation; and regulation of protein stability. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Mosmo |
| Official Name | modulator of smoothened [Source:RGD Symbol;Acc:7606925] |
| Ensembl ID | ENSRNOG00000061899 |
| Bio databases IDs | |
| Aliases | modulator of smoothened |
| Synonyms | ATTHOG, BC030336, C16orf52, LOC100360447, LOC100506442, modulator of smoothened |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mosmo often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Attenuator of Hedgehog
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- diminished ovarian reserve
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cilia
- Plasma Membrane
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mosmo gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein stability
- cell differentiation
- regulation of neuron differentiation
- negative regulation of smoothened signaling pathway
Cellular Component
Where in the cell the gene product is active
- cilium membrane
- Golgi apparatus
- plasma membrane