Hs3st3a1 Gene Summary [Mouse]

Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase activity. Involved in branching involved in ureteric bud morphogenesis and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and respiratory system. Orthologous to human HS3ST3A1 (heparan sulfate-glucosamine 3-sulfotransferase 3A1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hs3st3a1
Official Name
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 [Source:MGI Symbol;Acc:MGI:1333861]
Ensembl ID
ENSMUSG00000047759
Bio databases IDs NCBI: 15478 Ensembl: ENSMUSG00000047759
Aliases heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
Synonyms 3Ost3a, heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1, heparan sulfate-glucosamine 3-sulfotransferase 3A1, heparan sulphate (glucosamine) 3-O-sulphotransferase 3A1, heparan sulphate-glucosamine 3-sulphotransferase 3A1, Hs3st3a, RGD1561262
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hs3st3a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • [heparan sulfate]-glucosamine 3-sulfotransferase 1
  • Sulfotransferase domain
  • enzyme
  • Sulfotransferase family

Pathways

Biological processes and signaling networks where the Hs3st3a1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • heparan sulfate proteoglycan
phenotypes
  • decreased total body fat amount
  • increased body length
  • increased circulating creatinine level
  • increased heart weight

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi membrane

Gene-Specific Assays for Results You Can Trust

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