Details
| Type | T-Cell Receptor Joining Gene |
| Official Symbol | Traj18 |
| Official Name | T cell receptor alpha joining 18 [Source:MGI Symbol;Acc:MGI:4440521] |
| Ensembl ID | ENSMUSG00000076911 |
| Bio databases IDs | |
| Aliases | T cell receptor alpha joining 18 |
| Species | Mouse, Mus musculus |
Pathways
Biological processes and signaling networks where the Traj18 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- Allograft Rejection Signaling
- Altered T Cell and B Cell Signaling in Rheumatoid Arthritis
- Antiproliferative Role of TOB in T Cell Signaling
- Autoimmune Thyroid Disease Signaling
- Calcium-induced T Lymphocyte Apoptosis
- CCR5 Signaling in Macrophages
- CD28 Signaling in T Helper Cells
- Cdc42 Signaling
- CTLA4 Signaling in Cytotoxic T Lymphocytes
- Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells
- Dendritic Cell Maturation
- FAK Signaling
- G Protein Signaling Mediated by Tubby
- Graft-versus-Host Disease Signaling
- iCOS-iCOSL Signaling in T Helper Cells
- IL-4 Signaling
- Lipid Antigen Presentation by CD1
- NF-κB Signaling
- Nur77 Signaling in T Lymphocytes
- OX40 Signaling Pathway
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- abnormal circulating interleukin-4 level
- abnormal cytokine secretion
- abnormal fat pad morphology
- abnormal interferon-gamma secretion
- abnormal liver morphology
- absent NK T cells
- decreased airway resistance
- decreased fasting circulating glucose level
- decreased fat cell size
- decreased inflammatory response
- decreased susceptibility to diet-induced obesity
- improved glucose tolerance
- increased insulin sensitivity