G6pd2

Enables glucose-6-phosphate dehydrogenase activity. Predicted to be involved in several processes, including monosaccharide metabolic process; negative regulation of cell growth involved in cardiac muscle cell development; and negative regulation of metabolic process. Predicted to be located in several cellular components, including centriolar satellite; cytoplasmic side of plasma membrane; and intracellular membrane-bounded organelle. Predicted to be active in cytosol. Is expressed in genitourinary system; nervous system; and nose. Human ortholog(s) of this gene implicated in anemia (multiple); cerebrovascular disease; diabetes mellitus; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse G6pd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.