Rnf113a2 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in RNA splicing; negative regulation of chemokine-mediated signaling pathway; and protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of U2-type precatalytic spliceosome. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 5. Orthologous to human RNF113A (ring finger protein 113A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnf113a2 |
| Official Name | ring finger protein 113A2 [Source:MGI Symbol;Acc:MGI:1913631] |
| Ensembl ID | ENSMUSG00000098134 |
| Bio databases IDs | |
| Aliases | ring finger protein 113A2 |
| Synonyms | 2310020H19Rik, Riken cDNA 2310020h19, ring finger protein 113A2, Rnf113a, Zinc finger, C3HC4 type (RING finger), Znf183 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf113a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- RING-type zinc-finger
- ubiquitin protein ligase activity
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- enzyme
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm