LOC100912013 Gene Summary [Rat]
Predicted to enable ATP binding activity. Predicted to be involved in regulation of inflammatory response. Predicted to be part of canonical inflammasome complex. Predicted to be active in cytoplasm. Orthologous to human NLRP4 (NLR family pyrin domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC100912013 |
| Official Name | NACHT, LRR and PYD domains-containing protein 4B-like [Source:RGD Symbol;Acc:6489396] |
| Ensembl ID | ENSRNOG00000015527 |
| Bio databases IDs | |
| Aliases | NACHT, LRR and PYD domains-containing protein 4B-like |
| Synonyms | AU022726, E330024M09, Nalp4b, Nalp-gamma, Nalp-γ, NLR family, pyrin domain containing 4B, RGD1559894 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc100912013 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NLRC4 helical domain HD2
- PAAD/DAPIN/Pyrin domain
- NOD2 winged helix domain
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat, ribonuclease inhibitor type
- Leucine rich repeat
- NACHT domain
- Death Domain Superfamily of protein-protein interaction domains
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- FIGLA
- tetradecanoylphorbol acetate
- Gstp1 (includes others)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm