Cd177 Gene Summary [Rat]

Predicted to enable calcium-dependent protein binding activity; integrin binding activity; and protease binding activity. Predicted to be involved in several processes, including neutrophil extravasation; positive regulation of superoxide anion generation; and regulation of vesicle-mediated transport. Predicted to be located in plasma membrane and tertiary granule membrane. Predicted to be active in plasma membrane raft. Orthologous to human CD177 (CD177 molecule). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cd177
Official Name
CD177 molecule [Source:RGD Symbol;Acc:1562941]
Ensembl ID
ENSRNOG00000022669
Bio databases IDs NCBI: 499099 Ensembl: ENSRNOG00000022669
Aliases CD177 molecule
Synonyms 1190003K14Rik, CD177 antigen, CD177 molecule, LOC100909700, Pdp3, RGD1562941
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cd177 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calcium-dependent protein binding
  • TFP_LU_ECD_LYPD4_rpt2_like
  • protease binding
  • integrin binding
  • TFP

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal neoplasia
  • gastrointestinal neoplasia
  • dextran sodium sulfate-induced colitis
regulated by
regulates
role in cell
  • proliferation
  • frequency

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • secretory granule membrane
  • tertiary granule membrane
  • membrane rafts

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.