Ang2 Gene Summary [Rat]
Predicted to enable RNA nuclease activity. Involved in cellular response to mechanical stimulus. Predicted to be located in nucleolus. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Orthologous to human ANG (angiogenin). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ang2 |
| Official Name | angiogenin, ribonuclease A family, member 2 [Source:RGD Symbol;Acc:1359373] |
| Ensembl ID | ENSRNOG00000025562 |
| Bio databases IDs | |
| Aliases | angiogenin, ribonuclease A family, member 2 |
| Synonyms | Ang, angiogenin, ribonuclease A family, member 2, LOC108348324, Raa2 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ang2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonuclease
- enzyme
- RNase_A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- smoothened agonist
- HIF1A
- sulfasalazine
- liraglutide
- PKHD1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown