Clec4b2 Gene Summary [Rat]

Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response. Predicted to act upstream of or within positive regulation of release of sequestered calcium ion into cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4C (C-type lectin domain family 4 member C). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Clec4b2
Official Name
C-type lectin domain family 4, member B2 [Source:RGD Symbol;Acc:1359354]
Ensembl ID
ENSRNOG00000027655
Bio databases IDs NCBI: 450222 Ensembl: ENSRNOG00000027655
Aliases C-type lectin domain family 4, member B2
Synonyms Aplra1, C-type lectin domain family 4, member B2, F830043G12Rik, mDCAR1
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Clec4b2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  • Lectin C-type domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • IL10
  • IL12 (complex)
role in cell
  • production in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • plasma membrane extracellular face

Gene-Specific Assays for Results You Can Trust

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