AC120486.2 Gene Summary [Rat]
Predicted to enable peptide antigen binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane and extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Unprocessed Pseudogene |
| Official Symbol | AC120486.2 |
| Official Name | RT1 class I, locus M1, 2 [Source:NCBI gene;Acc:414786] |
| Ensembl ID | ENSRNOG00000031065 |
| Bio databases IDs | |
| Aliases | RT1 class I, locus M1, 2 |
| Synonyms | H2-M1, H2-M9, H2-Qa-Mb1, histocompatibility 2, M region locus 1, histocompatibility 2, M region locus 9, M9, Mb1, RT1 class I, locus M1, gene 2, RT1-M1-2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ac120486.2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin C1-set domain
- Class I Histocompatibility antigen, domains alpha 1 and 2
- MHC class I protein binding
- natural killer cell lectin-like receptor binding
- TAP binding
- immunoglobulin domain
- T-cell receptor binding
- receptor binding
- chaperone binding
- peptide antigen binding
- beta-2-microglobulin binding
Pathways
Biological processes and signaling networks where the Ac120486.2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- Golgi Apparatus
- Endoplasmic Reticulum