Fam81a Gene Summary [Rat]

Predicted to enable molecular condensate scaffold activity. Located in postsynaptic density. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Orthologous to human FAM81A (family with sequence similarity 81 member A). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fam81a
Official Name
family with sequence similarity 81, member A [Source:RGD Symbol;Acc:1311958]
Ensembl ID
ENSRNOG00000057501
Bio databases IDs NCBI: 315789 Ensembl: ENSRNOG00000057501
Aliases family with sequence similarity 81, member A
Synonyms 6430514L14Rik, family with sequence similarity 81 member A, family with sequence similarity 81, member A, MGC26690, RGD1311958
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam81a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding activity, bridging
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • alcoholism
  • COVID-19
  • periodontal pocket
regulated by
  • JAK1/2
  • levodopa
  • SNCA

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • glutaminergic synapse
  • organelle
  • Cytoplasm
  • postsynaptic density

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fam81a gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.