QIAseq Viral Safety and Clearance

For targeted enrichment and next-generation sequencing to support viral safety evaluation of biopharmaceutical products

  • Enrich diverse viral genomes from complex bioprocess samples using probe-based hybrid capture
  • Detect low-abundance viral sequences in high host-background matrices
  • Identify genetically diverse or emerging strains through mismatch-tolerant enrichment
  • Support RNA, DNA or total nucleic acid from cell banks, bulk harvest or raw materials
  • Align with risk-based viral safety evaluation strategies consistent with ICH Q5A(R2) principles

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Resources

Protocols (3)
The QIAseq xHYB MAP/RAP/HAP Panel enables sensitive detection of adventitious viruses aligned with ICH guidelines using hybrid capture–based targeted sequencing. It delivers high sensitivity at low copy numbers while providing strong genome coverage, making it a reliable and scalable alternative to traditional viral safety testing methods.
Pretreatment of respiratory samples
Technical Information (1)
Safety Data Sheets (1)
Download Safety Data Sheets for QIAGEN product components.
Certificates of Analysis (1)