Fbxl15 Gene Summary [Rat]
Involved in bone mineralization. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL15 (F-box and leucine rich repeat protein 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fbxl15 |
| Official Name | F-box and leucine-rich repeat protein 15 [Source:RGD Symbol;Acc:1306444] |
| Ensembl ID | ENSRNOG00000019509 |
| Bio databases IDs | |
| Aliases | F-box and leucine-rich repeat protein 15 |
| Synonyms | 0710008C12Rik, Fbl15, F-box and leucine-rich repeat protein 15, FBXO37, JET, PSD, RGD1306444 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fbxl15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- F-box domain superfamily
- Leucine-rich repeat - CC (cysteine-containing) subfamily
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fbxl15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of BMP signaling pathway
- G2/M transition of mitotic cell cycle
- bone mineralization
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
- dorsal/ventral pattern formation
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- SCF ubiquitin ligase complex
Molecular Function
What the gene product does at the molecular level
- protein binding