DANCR Gene Summary [Human]
This gene produces a long non-coding RNA that functions as a negative regulator of cell differentiation. This transcript associates with enhancer of zeste homolog 2 to repress expression of the runt related transcription factor 2 gene. Increased expression of this transcript may be associated with cancer. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2016]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | DANCR |
| Official Name | differentiation antagonizing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:28964] |
| Ensembl ID | ENSG00000226950 |
| Bio databases IDs | |
| Aliases | differentiation antagonizing non-protein coding RNA, anti-differentiation ncRNA, adipogenesis up-regulated transcript 2, anti-differentiation noncoding RNA |
| Synonyms | 2700023E23Rik, AGU2, ANCR, differentiation antagonizing non-protein coding RNA, KIAA0114, lncRNA-ANCR, SNHG13 |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- metastasis
- neoplasia
- epithelial cancer
- cancer
- diabetes mellitus
- gastric cancer
- colorectal cancer
- organismal death
- glioma formation
role in cell
- migration
- phosphorylation in
- autophagy in
- expression in
- formation in
- proliferation
- apoptosis
- number
- quantity
- cell cycle progression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown