GeneGlobe ID: UHS-5000Z | Cat. No.: Varies | QIAseq Multimodal Panels
QIAseq Multimodal Human Pan Cancer Panel
Product Specification
Kit containing ALL reagents (except indexes) for multimodal (DNA and RNA) sequencing
Target List
For DNA sequencing, covers all exons in all known transcripts of targeted genes based on the Human GRCh37 / hg19 genome build. For RNA sequencing, covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.
Bladder Cancer
Brain Cancer
Breast Cancer:
Basal (Triple-Negative) Carcinomas
Ductal Carcinomas
Other Carcinomas
Cervical Cancer
Colorectal Cancer
Adenocarcinomas
Lynch Syndrome
Gastric Cancer
Leukemia
Acute Lymphoblastic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
ASXL1ATMBCORBCORL1BIRC3BRAFCALRCARD11CDKN2ACEBPACHEK2CREBBPCSF1RCSF3RCTCFDAXXDDX41DNMT1EP300FLT3GATA1GATA2HNRNPKIDH1IDH2IKZF1IL7RJAK1JAK3KDM6AKDRKITKMT2AKMT2CKRASMAP2K1MPLMSH6MYCNBNANKRD26NOTCH1NPM1NRASNSD1NTRK3PDGFRAPHF6PTENPTPN11RAD21RUNX1SMARCB1SMC1ASMC3SRSF2STAG2U2AF1WT1ABL1ALKERGFGFR1JAK2KMT2AMLLT3NTRK3PDGFRAPDGFRB
Chronic Myeloid Leukemia (CML)
Liver Cancer
Lung Cancer
Non-Small Cell Lung Cancers (NSCLC)
Small Cell Lung Cancer
Adenocarcinomas
AKT1ALKAMER1APCARID1AATMBAP1BRAFCDKN2ACDKN2BCREBBPCTNNB1DDR2EGFREPHA5ERBB2ERBB4FBXW7FGFR1FGFR2FGFR3HRASJAK2KDRKEAP1KITKMT2DKRASLRP1BMAP2K1MDM2METMGAMLH1MYCNF1NFE2L2NOTCH1NRASNTRK1NTRK2NTRK3PDGFRAPIK3CAPIK3CGPIK3R1PIK3R2PTENPTPRDRB1RBM10RETRIT1ROS1RUNX1T1SETD2SMAD4SMARCA4SOX2STK11TNFAIP3TP53TSC1U2AF1ALKBRAFEML4ERBB2FGFR2FGFR3KIF5BMETNRG1NTRK1NTRK2RETROS1RPS6KB1
Squamous Cell Carcinomas (SCC)
AKT1ALKAMER1APCARID1AATMBRAFCDKN2ACDKN2BCREBBPCTNNB1DDR2EGFREPHA5ERBB2ERBB4FBXW7FGFR1FGFR2FGFR3HRASJAK2KDRKEAP1KITKMT2DKRASLRP1BMAP2K1MDM2METMGAMLH1MYCNF1NFE2L2NOTCH1NRASNTRK1NTRK2NTRK3PDGFRAPIK3CAPIK3CGPIK3R1PIK3R2PTENPTPRDRB1RBM10RETRIT1ROS1RUNX1T1SETD2SMAD4SMARCA4STK11TNFAIP3TP53TSC1U2AF1ALKEML4ERBB2FGFR2FGFR3KIF5BKITNRG1RET
Melanoma
Myeloid Neoplasms
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Other Myeloid Neoplasms
NUT Midline Carcinoma
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer
Sarcoma
Thyroid Cancer
Oncogenes
ABL1AKT1AKT2ALKARBCL2BCL2L1BCL2L1BCL2L1BRAFCARD11CASP8CBLCDK4CRKLCRLF2CSF1RCTNNB1DNMT3AEGFRERBB2ESR1ETS1EZH2FGFR2FGFR3FLT3FOXL2GATA2GNA11GNAQGNASH3-3AHGFH3C2HRASIDH1IDH2IKBKEJAK1JAK2JAK3JUNKITKRASMAP2K1MCL1MDM2MED12METMPLMYBMYCMYCNMYD88NFE2L2NFKBIANRASPDGFRAPIK3CAPPP2R1APTPN11RAF1RARARELRETROS1RUNX1SETBP1SF3B1SMOSPOPSRCSRSF2STAT3TSHRU2AF1
Tumor Suppressor Genes
ACVR1BAMER1APCARID1AARID1BARID2ARID5BASXL1ASXL2ATMATRXAXIN1B2MBAP1BARD1BCORBRCA1BRCA2CDC73CDH1CDKN2ACDKN2BCEBPACICCREBBPCYLDDAXXEP300FAT1FBXW7FLCNFOXP1FUBP1GATA1GATA3HNF1AKDM5CKDM6AKMT2CKMT2DMAP3K1MEN1MLH1MSH2MSH6NF1NF2NOTCH1NOTCH2NPM1PAX5PBRM1PHF6PIK3R1PRDM1PTCH1PTENRB1RNF43SETD2SMAD2SMAD4SMARCA4SMARCB1SOCS1SOX9STAG2STK11TET2TNFAIP3TP53TSC1TSC2VHLWT1ZFHX3
Receptor Tyrosine Kinases
Cancer Therapeutic Targets
Angiogenesis
Apoptosis
ABL1ABL2ACVR1AKT1AKT2AKT3APCARAFATMAXIN1BARD1BBC3BCL2BCL2L1BCL2L1BCL2L1BCL2L11BCL2L2BCL6BIRC3BRAFBRCA1BTG1CASP8CBLCDH1CDKN1ACDKN1BCDKN2ACHEK2CTNNA1CTNNB1CXCR4CYLDDAXXEGFREP300ERBB2ERBB3ETV1FASFLT3FOXL2GATA1HGFHRASID3IGF1IGF1RIL10IRS1JUNKRASMAP2K1MAP2K4MAPK1MAPK3MCL1MDM4MLH1MSH2MYCMYCNNF1NFKBIANPM1NUP93PDK1PIK3R2PIM1PRKCIPRKDCPTENRAD21RAD50RAD51RAF1RASA1RB1RELRHOARYBPSNCAIPSOX9STAT3STK11TERTTNFAIP3TOP2ATP53TRAF2TRAF7VEGFAVHLWT1XIAP
Autophagy
Cell Adhesion Molecules
Cell Cycle
ABL1ABL2ACVR1AKT1AKT2AKT3APCATMATRAURKAAURKBAXIN1BCL2BCRBLMBRCA1BRCA2BRD4CCND1CCND2CCND3CCNE1CDC73CDK12CDK4CDK6CDK8CDKN1ACDKN1BCDKN2ACDKN2BCDKN2CCENPACHEK1CHEK2CREBBPCUL3CUX1CYLDDIS3EGFREP300FBXW7FGFR2HGFHRASID3IGF1IGF2INHBAJAK2JUNKLF4KRASMAPK1MAPK3MDC1MDM2MDM4MEN1MLH1MYCNBNNF2NOTCH2NPM1NRASPDK1PIM1PLK2PPM1DPTENPTPRDRAD21RAD50RAD51RB1RHEBRHOASMARCA4SMARCB1SMC1ASMC3SOX2SOX9STAG1STAG2STK11TCF3TERTTNFAIP3TP53TSC1VEGFAXPO1ZFHX3
Cell Growth & Proliferation
Cell Migration
Cellular Senescence
DNA Damage & Repair
ABL1ABL2APCATMATRATRXAXIN2BARD1BLMBRCA1BRCA2BRIP1C11orf30CCND1CDKN1ACHEK1CHEK2EP300EPCAMERCC1ERCC2ERCC3ERCC4ERCC5ABRAXAS1FANCAFANCCFANCD2FANCEFANCFFANCGFANCIFANCLGEN1MAPK1MDC1MDM2MEN1MLH1MRE11MSH2MSH3MSH6MTORMUTYHNBNNPM1PALB2PARP1PIK3C2BPMS1PMS2POLD1POLEPRKDCRAD21RAD50RAD51RAD51BRAD51CRAD51DRAD52RAD54LRECQL4SETD2SMC1ASMC3STK11TERTTP53XIAPXRCC2
Epigenetics
ARID1AARID1BARID2ARID5BASXL1ASXL2ATRXAURKAAURKBBAP1BCORBCORL1BRD4CENPACHD2CHD4CTCFDICER1DNMT1DNMT3ADNMT3BDOT1LEEDEZH2FOXA1H3-3AH3F3BH3F3CHIST1H1CHIST1H2BDHIST1H3AH3C2HIST1H3CH3C4HIST1H3EHIST1H3FHIST1H3GHIST1H3HHIST1H3IHIST1H3JHIST2H3AHIST2H3CHIST2H3DHIST3H3IKZF1KAT6AKDM5AKDM5CKDM6AKMT2AKMT2BKMT2CKMT2DMLLT3NCOR1NSD1PBRM1PHF6PRDM1RARARUNX1T1RYBPSETBP1SETD2SMARCA4SMARCB1SMARCD1SPOPSUZ12TCF3TET1TET2TOP1
Growth Factors & Receptors
Immune Checkpoint Molecules
Immune Response
Metabolism
Signal Transduction
G-Protein Signaling
JAK / STAT Signaling & Targets
MAP Kinase Signaling & Targets
mTOR Signaling
NFκB Signaling & Targets
Notch Signaling & Targets
p53 Signaling & Targets
PI3K-AKT Signaling
TGFβ / BMP Signaling & Targets
WNT Signaling & Target
Telomeres & Telomerase
Transcription Factors
ABL1AKT1ARBRCA1BRCA2C11orf30CBLCDKN2ACEBPACHD4CICCREBBPCTNNB1CUX1DAXXEGFREIF4EEP300ERGESR1ETS1ETV1ETV4ETV5ETV6EWSR1FBXW7FLI1FOXA1FOXL2FOXO1FOXP1FUBP1GATA1GATA2GATA3GATA4GATA6GLI1HNF1AHOXB13ID3IRF4JUNKEAP1KLF4LMO1LZTR1MAXMDM2MEF2BMEN1MITFMLLT3MYBMYCMYCLMYCNMYOD1NF1NFE2L2NKX2-1NKX3-1NOTCH1PAX5PGRPHOX2BPNRC1PPARGRARARB1RELRUNX1SMAD2SMAD3SMAD4SOX10SOX17SOX2SOX9STAT3STAT5ASUFUTAF1TBX3TCEB1TCF3TCF7L2TOP1TP53TSC1VHLWT1ZBTB2ZBTB7AZFHX3ZNF217ZNF703
Microsatellite Instability (MSI) Loci
BAT25BAT26BAT34C4BAT40D10S196D13S175D17S250D17S588D17S787D18S35D18S55D18S61D18S64D18S69D20S100D2S123D3S1029D5S107D5S346D7S519D8S87HSP110-T17MONO-27NR21NR22NR24
Breast Cancer
Lymphoma
Other Cancers
Soft Tissue Cancer
Inflammatory Myofibroblastic Tumors
Product Resources
File Size: 32.85 KBLanguage: English
File Size: 478.51 KBLanguage: English
Resources
Template Files (6)
Brochures & Guides (4)
Kit Handbooks (2)
Supplementary Files (1)
Safety Data Sheets (1)
Certificates of Analysis (1)
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