Faim Gene Summary [Mouse]
Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in cytoplasm. Is expressed in several structures, including gonad; hemolymphoid system; intestine; liver; and retina. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Faim |
| Official Name | Fas apoptotic inhibitory molecule [Source:MGI Symbol;Acc:MGI:1344387] |
| Ensembl ID | ENSMUSG00000032463 |
| Bio databases IDs | |
| Aliases | Fas apoptotic inhibitory molecule |
| Synonyms | Faim-L, Fas apoptotic inhibitory molecule |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Faim often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fas apoptotic inhibitory molecule (FAIM1)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- perikaryon
- dendrites