Gpr63 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of receptor complex. Is expressed in gut; male reproductive gland or organ; metanephros; nervous system; and thymus. Orthologous to human GPR63 (G protein-coupled receptor 63). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Gpr63
Official Name
G protein-coupled receptor 63 [Source:MGI Symbol;Acc:MGI:2135884]
Ensembl ID
ENSMUSG00000040372
Bio databases IDs NCBI: 81006 Ensembl: ENSMUSG00000040372
Aliases G protein-coupled receptor 63
Synonyms G protein-coupled receptor 63, Psp24-2, PSP24B, PSP24beta, PSP24(beta), PSP24(β)
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr63 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (rhodopsin family)
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gpr63 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • idiopathic scoliosis
  • ischemic stroke
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr63 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • receptor complex
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.